Plant Transcription Factor Database
Previous version: v3.0
Spinacia oleracea
ARF Family
Species TF ID Description
Sp_005380_smnq.t1ARF family protein
Sp_009550_amof.t1ARF family protein
Sp_009550_amof.t2ARF family protein
Sp_019820_smzt.t1ARF family protein
Sp_038740_sosp.t1ARF family protein
Sp_048190_wgha.t1ARF family protein
Sp_048190_wgha.t2ARF family protein
Sp_048190_wgha.t3ARF family protein
Sp_094090_guao.t1ARF family protein
Sp_094480_jsmt.t1ARF family protein
Sp_121260_adfm.t1ARF family protein
Sp_121730_ewts.t1ARF family protein
Sp_123070_uudr.t1ARF family protein
Sp_140590_pcst.t1ARF family protein
Sp_141030_hqpq.t1ARF family protein
Sp_146820_ahao.t1ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969